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Does It Work for Weight Loss ?

Dietrine was designed to block carb absorption, by inhibiting the pancreatic enzyme alpha-amylase which breaks down starches into simple sugars in the small intestine. Starches cannot be absorbed through the intestinal wall without being disassembled into simple sugars, since their molecules are too big to pass through. Therefore, inhibiting the enzyme alpha-amylase will result in a lower percent of carbohydrates being absorbed with each meal.

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Here's a list of the main ingredients in Dietrine:

  • White Kidney Bean Extract (the so-called "Phase 2®" component), which is the key ingredient of this weight loss supplement
  • Chromium
  • Vanadium

Mechanism of Action:

  • As discussed above, the Phase 2® component partially blocks the intestinal absorption of carbs.
  • Chromium and Vanadium intervene in the metabolism of glucose, promoting optimal utilization and thus decreasing blood glucose levels. This in turn helps prevent insulin spikes which lead to the formation and accumulation of fat deposits.
  • Chromium may also have a moderate appetite suppressant effect.

So Does It Work for Weight Loss?

Given the strong association between increased blood glucose levels and obesity, we feel the principle of the Dietrine formula is sound. Moreover, the clinical studies conducted so far appear to be promising: Subjects reportedly lost on average 3.8 lbs in 8 weeks, and experienced a significant decrease in triglyceride levels, as well as a subjective increase in energy levels. A detailed report of the clinical studies conducted is posted on the official Dietrine site.

Analyzing the above data, it seems somewhat disappointing the subjects only lost 3.8 pounds in 2 months. However, the decrease in triglyceride levels (saturated fat circulating in the bloodstream) is quite promising and suggests this supplement may have beneficial effects on one's health beyond weight control.

At this point, it seems that further clinical studies with larger numbers of subjects will be needed to document the true efficacy of Dietrine as a weight loss agent. In the meantime, this product may be used as a safe pharmaceutical adjunct to a proper diet and exercise program.

One word of warning must be included here: One should never rely on taking a "carb blocker" to justify dietary indulgences. Dietrine's inhibitory effect on the pancreatic enzyme that breaks down starches is not 100%. Moreover, the production of this enzyme is stimulated by intake of high-carb foods, which may thus negate the effects of Dietrine.

Side Effects:

  • According to the manufacturer, Dietrine is generally well tolerated and safe for long-term use.
  • When tested in clinical studies, it reportedly did not produce any significant side effects, except possibly excess gas.


The recommended dosage is 2 capsules prior to starchy meals, once or twice a day.


  • Dietrine may be purchased online, from the manufacturer and other sources, for about $40 per bottle (60 tablets), plus shipping and handling fee.
  • The manufacturer offers a discount if purchasing multiple bottles, as well as an autoshipment discount.
  • The official site offers a 90 day money back guarantee, which is nice to have and makes a statement as to the quality of the product. On second thought, this also lets you know not to expect dramatic weight loss results in the first month or two of usage.


Note: Please be aware that any weight loss supplement may be associated with certain side effects and/or health risks. It is prudent to talk to your physician prior to using this or any other weight loss product, especially if you are taking other medication, suffer from a preexisting medical condition, or are pregnant or breast-feeding.

Disclaimer: Although the information on this page is correct to the best of our knowledge, its accuracy and completion are not guaranteed. Prior to using this or any other weight loss supplement, please refer to the instructions included by the manufacturer with the product purchased.

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