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Does It Work for Weight Loss ?

First, let me start out by saying that the official Cortislim website, which during my last visit in December of 2007 was up and running, appears to have been dismantled in the meantime. Of course, this doesn't bode well for the reliability of the company or the product. It has also come to my attention that the makers of Cortislim were charged by the Federal Trade Commission (FTC) for making false or unsubstantiated allegations, and settled the case for 4.5 million dollars in September 2005. You may use this link for further details regarding this action. This being said, lets turn our attention to the product and evaluate it on its own merits:

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The Cortislim formula is tackling weight control from a different (and in all fairness, rather innovative) angle. This product is supposed to reduce stress levels and decrease the body's secretion of the hormone cortisol.

Cortisol is a hormone routinely produced by our body in response to high stress situations. It's a documented scientific fact that cortisol increases blood glucose levels and promotes the formation and accumulation of fat, especially around the midsection and on the face and neck. So, while eating the same diet, persons with a higher cortisol level will transform more of the aliments ingested into body-fat than persons with a lower cortisol level.

Mechanism of Action:

  • Cortislim contains Magnolia Bark, which has anti-anxiety effects probably due to the 'honokiol' in its composition. The hypothesis is that decreasing background anxiety will result in decreased cortisol levels.
  • When tested in animal studies, Honokiol has indeed been shown to reduce cortisol levels. As such, it seems plausible that it would have the same effect in humans, although to my knowledge no controlled studies have been conducted in humans.

Here's a list of the main ingredients in Cortislim:

  • Honokiol (from Magnolia Bark)
  • Green Tea extract – with antioxidant and thermogenic (fat-burning) properties
  • Chromium - a microelement which helps maintain stable blood glucose levels, thus preventing insulin spikes which lead to the formation and accumulation of fat deposits.
  • L-theanine - an aminoacid which promotes Serotonin release to improve mood and energy levels
  • Vanadyl Sulfate Citrus - a compound which regulates and optimizes blood glucose levels
  • Vitamin C and Calcium - both of which are required for multiple metabolic processes
  • Citrus Aurantium (bitter orange) - a metabolic stimulant containing the active ingredient 'Synephrine', which is believed to have fat-burning properties similar to Ephedrine but allegedly less cardiovascular

Several Cortislim formulations are currently available on the market, and depending on the specific formulation, ingredients and amounts may vary slightly.

So How Effective Is It for Weight Loss?

In order to avoid disappointment, it's important to recognize that Cortislim is no miracle drug which simply melts the pounds away. This product can be helpful as an adjunct to a proper diet and exercise program, in persons who are dealing with high daily stress in their lives. Honokiol, the active ingredient in Cortislim, supposedly has anti-anxiety effects comparable to those of Valium (a prescription benzodiazepine agent), without the marked sedative effects of Valium. In other words, Honokiol will relieve stress and anxiety without making you sleepy.

Side Effects:

The Cortislim formula contains Synephrine (from bitter orange) and green tea extract - both compounds with metabolic stimulant effect, which can occasionally induce jitteriness, irritability and insomnia. As with all products containing metabolic stimulants, there is a possibility of developing increased heart rate and blood pressure, as well as certain gastrointestinal side effects (such as nausea, upset stomach, and diarrhea).


The dose recommended by the manufacturers is 1-2 tablets with meals, 2-3 times a day, not to exceed a maximum of 6 tablets per day.


Cortislim is widely available in stores and online. Prices differ - from $20 to $40 for 180 tablets, which is fairly inexpensive compared to other weight loss drugs.


Please note: This product is for the use of adults only. Pregnant or nursing women should not take this product. Please be aware that any weight loss supplement may be associated with certain side effects and/or health risks. It is prudent to talk to your physician prior to using this or any other weight loss product, especially if you are taking other medication or suffer from a preexisting medical condition.

Disclaimer: Although the information on this page is correct to the best of our knowledge, its accuracy and completion are not guaranteed. Prior to using this or any other weight loss supplement, please refer to the instructions included by the manufacturer with the product purchased.

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